Mesothelioma and Work Exposure People who work with asbestos are at higher risk of developing mesothelioma. Construction workers, firefighters and veterans of the military are at higher risk. Mesothelioma primarily affects the lung's lining (pleural mesothelioma) or abdomen. In rare cases, it can affect the testicles and the heart. Consult https://vimeo.com/705027215