No effect of polymorphisms in catechol-O-methyltransferase was located being involved with postoperative oxycodone intake. The pharmacodynamics of oxycodone is generally dependent on polymorphic enzymes CYP2D6 and CP3A. gene encodes the key receptor target for many opioids. The most important and up to date genome-vast Affiliation analyze in adults recognized OPRM1 https://wockusa.com/