During embryogenesis. the mammalian heart develops from a primitive heart tube originating from two bilateral primary heart fields located in the lateral plate mesoderm. Cells belongings to the pre-cardiac mesoderm will differentiate into early cardiac progenitors. which express early transcription factors which are also common to the Isl-1 positive cardiac progenitor cells isolated f... https://www.chiggate.com/jerome-brown-philadelphia-eagles-mitchell-ness-1990-legacy-jersey-discount/